David Wootton

Associate Professor of Mechanical Engineering

Peer-Reviewed Journal Papers (2012 - 1999)

  1. Wootton DM, Alevriadou BR.  “The shear stress of busting blood clots,” New England Journal of Medicine. 2012 Oct 4;367(14):1361-3.  [link]
  2. Lu L, Zhang Q, Wootton D, Chiou R, Li D, Lu B, Lelkes P, Zhou J.  “Mechanical Study on Polycaprolactone-Hydroxyapatite Porous Scaffolds by Porogen-Based Solid Freeform Fabrication Method,” Journal of Applied Biomaterials and Biomechanics, in press
  3. Lu L, Zhang Q, Wootton D, Chiou R, Li D, Lu B, Lelkes P, Zhou J.  “Biocompatibility and biodegradation studies of PCL/b-TCP bone tissue scaffold fabricated by structural porogen method,” Journal of Materials Science: Materials in Medicine, 2012 Sep;23(9):2217-26.  [abstract].
  4. Persak SC, Sin S, McDonough JM, Arens R, Wootton DM. “Noninvasive estimation of pharyngeal airway resistance and compliance in children based on volume-gated dynamic MRI and Computational Fluid Dynamics,” Journal of Applied Physiology. 2011 Dec;111(6):1819-27. [abstract]
  5. Arens R, Sin S, Nandalike K, Rieder J, Khan U, Freeman K, Wylie-Rosett J, Lipton M, Wootton DM, McDonough JM, Shifteh K. “Upper Airway Structure and Body Fat Composition in Obese Children With Obstructive Sleep Apnea Syndrome,” American Journal of Respiratory and Critical Care, 2011 Mar 15;183(6):782-7. [abstract]
  6. Arens R, Sin S, Willen S, Bent J, Parikh SR, Freeman K, Wootton DM, McDonough JM, Shifteh K.  “Rhino-sinus involvement in children with obstructive sleep apnea syndrome,” PediatricPulmonology. 2010 Oct;45(10):993-8. [abstract]
  7. Lu, Lin, Zhang, Qingwei, Wootton, David, Lelkes, Peter, and Zhou, Jack, “A novel sucrose porogen-based solid freeform fabrication system for bone scaffold manufacturing,” Rapid Prototyping Journal,  V. 16, #5, pp. 365-376, 2010. [abstract]
  8. Xu C, Brennick MJ, Dougherty L, Wootton DM, “Modeling of Upper Airway Collapse by Regional Tissue Properties in a Finite Element Model,” Medical Engineering and Physics, V. 31, #10, pp. 1343-1348, 2009. [abstract]
  9. Marcus C, Smith RJH, Mankarious L, Arens R, Mitchell G, Elluru RG, Forte V, Goudy S, Jabs EW, Katz E, Paydarfar D, Reeves RH, Richtsmeier JT, Ruiz RL, Thach BT, Tunkel DE, Whitsett JA, Wootton D, Blaisdell CJ, “Developmental Aspects of the Upper Airway, Report from an NHLBI Workshop March 5-6, 2009.”  Proceedings of the American Thoracic Society, V. 6, #6, pp. 513-520, 2009. [abstract]
  10. Zhou J, Lu L, Byrapogu K, Wootton DM, Lelkes PI, Fair R, “Electrowetting-based multi-microfluidics array printing of high resolution tissue construct with embedded cells and growth factors,” Virtual and Physical Prototyping, V. 2, #4, pp. 217-223, 2007. [abstract]
  11. Ergezen E, Appel M, Shah P, Kresh JY, Lec RM, Wootton DM, “Real-Time Monitoring of Adhesion and Aggregation of Platelets using Thickness Shear Mode (TSM) Sensor,” Biosensors and Bioelectronics, V. 23, #4, pp. 575-82, 2007. [abstract]
  12. Mondrinos M, Dembzymsky R, Lu L, Byrapogu, VKC, Wootton DM, Lelkes PI, Zhou GJ, “A Porogen-based Solid Freeform Fabrication of Polycaprolactone-Calcium Phosphate Scaffolds for Tissue Engineering,” Biomaterials, V. 27, #25, pp. 4399-4408, 2006. [abstract] 
  13. Xu C, Sin S, McDonough M, Udupa JK, Arens R, Guez A, Wootton DM,  “Computational Fluid Dynamics Modeling of the Upper Airway of Children with Obstructive Sleep Apnea Syndrome in Steady Flow,” Journal of Biomechanics, V. 39, #11, pp. 2043-2054, 2006. [abstract]
  14. Arens R, Sin S, McDonough JM, Palmer J, Dominguez T, Meyer H, Wootton DM, Pack AI, “Changes in Upper Airway Size during Tidal Breathing in Children with Obstructive Sleep Apnea Syndrome,” Am. Journal of Respiratory and Critical Care, V. 171, #11, pp. 1292-1297. 2005. [abstract]
  15. Xu C, Wootton DM, “Platelet Near-Wall Excess in Porcine Whole Blood in Artery-Sized Tubes Under Steady and Pulsatile Flow Conditions”, Biorheology, V. 41, pp 113-125, 2004. [abstract] 
  16. Wootton DM, Popel AS, Alevriadou BR, “An Experimental and Theoretical Study on the Dissolution of Mural Fibrin Clots by Tissue-Type Plasminogen Activator,” Biotechnology and Bioengineering, V. 77, #4, pp. 405-419, 2002. [abstract]
  17. Wootton DM, Markou CP, Hanson SR, Ku DN, “A Mechanistic Model of Acute Platelet Accumulation in Thrombogenic Stenoses,” Annals of Biomedical Engineering, V. 29, pp. 321-329, 2001. [abstract]
  18. Jerius H, Karolyi DR, Mondy JS, Beall A, Wootton D, Ku D, Cable S, Brophy CM, “Endothelial-dependent vasodilation is associated with increases in the phosphorylation of a small heat shock protein (HSP20)”, Journal of Vascular Surgery, V. 29, pp. 678-84, 1999.
  19. Wootton DM, Ku DN,  “Fluid Mechanics of Vascular Systems, Diseases, and Thrombosis,” Annual Review of Biomedical Engineering,  V. 1, pp. 299-329, 1999. [abstract]