Eric Lima

Assistant Professor of Mechanical Engineering

Publications

Kelly TA, Roach BL, Weidner ZD, Mackenzie-Smith CR, O'Connell GD, Lima EG, Stoker AM, Cook JL, Ateshian GA, Hung CT. Tissue-engineered articular cartilage exhibits tension-compression nonlinearity reminiscent of the native cartilage. J Biomech. 2013 Jul 26;46(11):1784-91. PubMed PMID: 23791084; PubMed Central PMCID: PMC3713158.

Lima EG, Durney KM, Sirsi SR, Nover AB, Ateshian GA, Borden MA, Hung CT. Microbubbles as biocompatible porogens for hydrogel scaffolds. Acta Biomater. 2012 Dec;8(12):4334-41. PubMed PMID: 22868194; PubMed Central PMCID: PMC3654399.

O'Connell GD, Lima EG, Bian L, Chahine NO, Albro MB, Cook JL, Ateshian GA, Hung CT. Toward engineering a biological joint replacement. J Knee Surg. 2012 Jul;25(3):187-96. PubMed PMID: 23057137; PubMed Central PMCID: PMC3700804.

Bian L, Fong JV, Lima EG, Stoker AM, Ateshian GA, Cook JL, Hung CT. Dynamic mechanical loading enhances functional properties of tissue-engineered cartilage using mature canine chondrocytes. Tissue Eng Part A. 2010 May;16(5):1781-90. PubMed PMID: 20028219; PubMed Central PMCID: PMC2952125.

Ng KW, Lima EG, Bian L, O'Conor CJ, Jayabalan PS, Stoker AM, Kuroki K, Cook CR, Ateshian GA, Cook JL, Hung CT. Passaged adult chondrocytes can form engineered cartilage with functional mechanical properties: a canine model. Tissue Eng Part A. 2010 Mar;16(3):1041-51. PubMed PMID: 19845465; PubMed Central PMCID: PMC2862612.

Lima EG, Tan AR, Tai T, Marra KG, DeFail A, Ateshian GA, Hung CT. Genipin enhances the mechanical properties of tissue-engineered cartilage and protects against inflammatory degradation when used as a medium supplement. J Biomed Mater Res A. 2009 Dec;91(3):692-700. PubMed PMID: 19025982; PubMed Central PMCID: PMC2767416.

Chahine NO, Albro MB, Lima EG, Wei VI, Dubois CR, Hung CT, Ateshian GA. Effect of dynamic loading on the transport of solutes into agarose hydrogels. Biophys J. 2009 Aug 19;97(4):968-75. PubMed PMID: 19686643; PubMed Central PMCID: PMC2726307.

Bian L, Angione SL, Ng KW, Lima EG, Williams DY, Mao DQ, Ateshian GA, Hung CT. Influence of decreasing nutrient path length on the development of engineered cartilage. Osteoarthritis Cartilage. 2009 May;17(5):677-85. PubMed PMID: 19022685; PubMed Central PMCID: PMC3387279.

Lima EG, Tan AR, Tai T, Bian L, Ateshian GA, Cook JL, Hung CT. Physiologic deformational loading does not counteract the catabolic effects of interleukin-1 in long-term culture of chondrocyte-seeded agarose constructs. J Biomech. 2008 Nov 14;41(15):3253-9. PubMed PMID: 18823628; PubMed Central PMCID: PMC2724593.

Lima EG, Grace Chao PH, Ateshian GA, Bal BS, Cook JL, Vunjak-Novakovic G, Hung CT. The effect of devitalized trabecular bone on the formation of osteochondral tissue-engineered constructs. Biomaterials. 2008 Nov;29(32):4292-9. PubMed PMID: 18718655; PubMed Central PMCID: PMC2562244.

Lima EG, Tan AR, Tai T, Bian L, Stoker AM, Ateshian GA, Cook JL, Hung CT. Differences in interleukin-1 response between engineered and native cartilage. Tissue Eng Part A. 2008 Oct;14(10):1721-30. PubMed PMID: 18611148.

Bian L, Lima EG, Angione SL, Ng KW, Williams DY, Xu D, Stoker AM, Cook JL, Ateshian GA, Hung CT. Mechanical and biochemical characterization of cartilage explants in serum-free culture. J Biomech. 2008;41(6):1153-9. PubMed PMID: 18374344; PubMed Central PMCID: PMC3387278.

Lima EG, Bian L, Ng KW, Mauck RL, Byers BA, Tuan RS, Ateshian GA, Hung CT. The beneficial effect of delayed compressive loading on tissue-engineered cartilage constructs cultured with TGF-beta3. Osteoarthritis Cartilage. 2007 Sep;15(9):1025-33. PubMed PMID: 17498976; PubMed Central PMCID: PMC2724596.

Lima EG, Bian L, Mauck RL, Byers BA, Tuan RS, Ateshian GA, Hung CT. The effect of applied compressive loading on tissue-engineered cartilage constructs cultured with TGF-beta3. Conf Proc IEEE Eng Med Biol Soc. 2006;1:779-82. PubMed PMID: 17946858.

Lima EG, Mauck RL, Han SH, Park S, Ng KW, Ateshian GA, Hung CT. Functional tissue engineering of chondral and osteochondral constructs. Biorheology. 2004;41(3-4):577-90. PubMed PMID: 15299288.

Hung CT, Mauck RL, Wang CC, Lima EG, Ateshian GA. A paradigm for functional tissue engineering of articular cartilage via applied physiologic deformational loading. Ann Biomed Eng. 2004 Jan;32(1):35-49. PubMed PMID: 14964720.

Hung CT, Lima EG, Mauck RL, Takai E, LeRoux MA, Lu HH, Stark RG, Guo XE, Ateshian GA. Anatomically shaped osteochondral constructs for articular cartilage repair. J Biomech. 2003 Dec;36(12):1853-64. PubMed PMID: 14614939.